Program

Please note that this program is subject to change.

Click here to download the program.

 

Monday, October 20

12:00

Vineyard excursion (reservation necessary)

16:00

Arrival and registration

18:00

Welcome reception and opening remarks

18:30

Introduction to Micronaut exhibition 
Henning Stahlberg, University of Basel

19:00

Keynote Lecture: Light-based systems biology
Gene Myers, Max Planck Institute for Molecular Cell Biology and Genetics (Germany)

Tuesday, October 21

Theory and Biophysical Modeling
Chair: Félix Naef, EPF Lausanne

09:00

Gradient scaling and growth control in Epithelia
Frank Jülicher, Max Planck Institute for Physics of Complex Systems (Germany)

09:50

Quantifying Nature's appearance: combining high-resolution, coloured 3D reconstruction and mathematical tools to analyse skin patterns in Pantherophis guttatus
Antonio Martins, University of Geneva (CH)

10:10

Automated reconstruction of genome-scale metabolic network models
Jörg Stelling, ETH Zurich (CH)

10:35

Break

11:00

What is the dimension of molecular recognition?
Tsvi Tlusty, Institute for Advanced Study Princeton (USA)

11:30

Robust Pom1 gradient formation through intermolecular phosphorylation in fission yeast
Micha Hersch, University of Lausanne (CH)

11:50

Computational dissection of phenotypic and functional heterogeneity in cancer
Dana Pe'er, Columbia University (USA)

12:35

Lunch and poster session

Quantitative Cell and Developmental Biology
Chair: Marcos Gonzalez-Gaitan, University of Geneva

14:15

A Doppler effect in embryonic patterning
Andrew Oates, National Institute for Medical Research (UK)

15:05

The in silico limb: a dynamic spatial model for the morpho-regulatory signalling during vertebrate organogenesis
Erkan Unal, University of Basel (CH)

15:25

Compression of ESCRT spiral springs induces lipid membrane buckling
Aurélien Roux, University of Geneva (CH)

15:50

Break

16:30

Genetic and neuronal networks mediating active forgetting
Simon Sprecher, University of Fribourg (CH)

17:00

Automated quantitative histology - a machine learning approach to quantify large-scale growth processes
Christian Hartke, University of Lausanne (CH)

17:20

Cortical contractility triggers a motile switch to fast amoeboid migration in 3D environments
Carl-Philipp Heisenberg, IST (Austria)

18:05

Drinks and poster session

Wednesday, October 22

Functional Genomics and Gene Regulation
Chair: Bart Deplancke, EPF Lausanne

09:00

How functional genomics elucidates global transcription mechanisms
Patrick Cramer, Max Planck Institute for Biophysical Chemistry (Germany)

09:50

Massive parallel genome engineering identifies transcription factor binding as a principal mechanism controlling DNA methylation states of CpG islands
Arnaud Krebs, Friedrich Miescher Institute (CH)

10:10

Expression noise facilitates the evolution of gene regulation
Erik van Nimwegen, University of Basel (CH)

10:35

Break

11:00

Recasting the net for miRNA targets and functions
Mihaela Zavolan, University of Basel (CH)

11:30

Systematic characterisation of the KRAB zinc finger protein family using high resolution ChIP-Seq
Michael Imbeault, EPF Lausanne (CH)
and
MITOMI-seq: a novel tool enabling the parallel characterisation of DNA binding specificities of TF monomers and heterodimers
Alina Isakova, EPF Lausanne (CH)

12:00

Synchronization of circadian and cell cycle oscillators in single mammalian cells
Félix Naef, EPF Lausanne (CH)

12:35

Lunch and poster session

Single-Cell Biology
Chair: Lucas Pelkmans, University of Zurich

14:15

Force scaling in stress fibers
Manuel Théry, iRTSV (France)

15:05

The Legionella pneumophila Lqs quorum sensing system - Phosphorylation signaling and intra-amoeba single cell gene regulation
Hubert Hilbi, University of Zurich (CH)

15:20

Break

16:00

A structural systems biology approach to cell biology by electron microscopy: Multiscale structural analysis from bulk tissue to the full proteome of a single cell
Henning Stahlberg, University of Basel (CH)

16:30

Noise facilitates NF-kappaB entrainment and transcriptional control under complex signalling environments
Savas Tay, ETH Zurich (CH)

16:50

It's Too Late to Apoptize: A time-dependent threshold for p53-mediated apoptosis
Galit Lahav, Harvard Medical School (USA)

17:20

Conference dinner (reservation necessary)

Thursday, October 23

Systems Genetics and Medicine
Chair: Olivier Michielin, University of Lausanne and Swiss Institute of Bioinformatics

09:00

Identifying therapeutic intervention points through systems genetics
Lars Steinmetz, EMBL (Germany)

09:50

Translating cancer genomes into effective personalised immunotherapies
Etienne Caron, ETH Zurich (CH)

10:10

Act Locally, Think Globally: Pathogen behaviour in complex host environments
Dirk Bumann, University of Basel (CH)

10:35

Break

11:00

Variation and genetic control of chromatin architecture in humans
Bart Deplancke, EPF Lausanne (CH)

11:30

Influence of L-arginine on metabolic networks and the lifespan of activated T cells
Roger Geiger, Università della Svizzera italiana (CH)

11:50

Poster awards

12:30

Keynote lecture: Architecture and dynamics of the Notch signalling pathway
Michael Elowitz, CALTECH (USA)

13:30

Lunch and departure

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