Invited Speakers

The following internationally renowned speakers have confirmed their participation in the 2nd International SystemsX.ch Conference.
 

Keynote Speakers

Michael Elowitz, California Institute of Technology, Pasadena, USA
Gene Myers, Max-Planck-Institute of Molecular Cell Biology and Genetics, Dresden, Germany

 

International Speakers

Patrick Cramer, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany
Carl-Philipp Heisenberg, Institute of Science and Technology, Klosterneuburg, Austria
Tim Hughes, University of Toronto, Canada
Frank Jülicher, Max-Planck-Institute for the Physics of Complex Systems, Dresden, Germany
Galit Lahav, Harvard Medical School, Boston, USA
Andrew Oates, National Institute for Medical Research, London, UK
Dana Pe’er, Columbia University, New York, USA
Lars Steinmetz, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
Manuel Théry, Institute of life sciences research and technologies (iRTSV), Grenoble, France
Tsvi Tlusty, Institute for Advanced Study, Princeton, USA

 

SystemsX.ch Speakers

Dirk Bumann, BattleX, University of Basel
Bart Deplancke, AgingX, Laboratory of Systems Biology and Genetics, Lausanne
Aurélien Roux, EpiPhysX, University of Geneva
Simon Sprecher, SynaptiX, University of Fribourg
Henning Stahlberg, CINA, University of Basel
Jörg Stelling, MetaNetX, Department of Biosystems Science and Engineering, Basel
Erik van Nimwegen, Cell Plasticity, Friedrich Miescher Institute for Biomedical Research, Basel
Mihaela Zavolan, StoNets, University of Basel

Click here to download the program.

 

 

 

Michael Elowitz

California Institute of Technology
Pasadena, USA

Website: The Elowitz Lab

Dynamic Gene Circuits at the Single-Cell Level

All cells use circuits of interacting genes and proteins to respond to stimuli, communicate with one another, and control their differentiation. Even when the components and regulatory interactions that compose these circuits are known, the design principles that govern circuit architecture usually remain mysterious. Michael Elowitz uses synthetic biology, time-lapse movies, and mathematical modeling to study gene circuit architecture and dynamics down to the level of individual cells. His laboratory works on problems in differentiation, cell-cell signaling, and stress response. He focuses particularly on the role that stochastic fluctuations (noise) play in living cells.

Elowitz is a professor of biology and applied physics at the California Institute of Technology and received in 2011 the HFSP Nakasone Award, Human Frontier Science Program Organization.

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Gene Myers

Max-Planck-Institute of Molecular Cell Biology and Genetics
Dresden, Germany

Website: Max-Planck-Institute

Human Whole Genome Shotgun Sequencing

In the 80's Gene Myers developed many efficient algorithms for sequence comparison and search, used, for example, in BLAST and UNIX diff. With Udi Manber, he invented suffix arrays that enable the Burroughs-Wheeler transform needed in todays space-efficient indices, especially for genomic data. Myers developed the overlap-layout-consensus paradigm for DNA sequencing, ultimately perfecting the string graph approach used at Celera to successfully assemble the fly, human, and mouse genomes. With Jim Weber, he was the first to propose paired-end whole genome shotgun sequencing of the human genome, the paradigm by which most genomes are sequenced today. Recently he has focused on the construction of novel microscopes and software for building single cell expression atlases across developmental epochs.

Myers has been a professor at U of Arizona and UC Berkeley, a vice president at Celera Genomics, and a group leader for HHMI and the Max-Planck Society. He is a member of the National Academy of Engineering, USA, the National Academy of Germany, and won the ACM Kannellakis Prize in 2002. 

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